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Symbol
Name
ID

Gbx2
gastrulation brain homeobox 2
MGI:95668

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Mouse Phenotypes

nervous system phenotype

decreased embryonic neuroepithelium thickness

abnormal neural crest cell morphology

decreased neural crest cell number

abnormal rhombomere 5 morphology

abnormal nervous system morphology

abnormal forebrain development

abnormal hindbrain development

abnormal cerebellum development

abnormal cerebellar foliation

abnormal midbrain development

abnormal midbrain-hindbrain boundary morphology

abnormal midbrain-hindbrain boundary development

abnormal choroid plexus morphology

abnormal midbrain morphology

abnormal inferior colliculus morphology

increased inferior colliculus size

abnormal pons morphology

abnormal locus ceruleus morphology

abnormal hindbrain morphology

abnormal metencephalon morphology

abnormal cerebellum morphology

cerebellum vermis hypoplasia

absent cerebellum

abnormal innervation

abnormal motor neuron morphology

abnormal cochlear ganglion morphology

absent cochlear ganglion

abnormal trigeminal ganglion morphology

fusion of glossopharyngeal and vagus nerve

absent trigeminal nerve

decreased embryonic neuroepithelial cell proliferation

Availability

Mouse Genotype

Gbx2^tm1.1Mrt/Gbx2^tm1.1Mrt

Gbx2^{tm1.1(cre/ERT2)Jyhl}/Gbx2^tm1.1Mrt

Gbx2^tm1.1Mrt/Gbx2^tm1.2Alj

En1^tm2(cre)Wrst/En1⁺
Gbx2^tm1.1Mrt/Gbx2^tm1.1Alj (conditional)

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Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23